2019 State of the Science Summit:
Paths to Treatment for Traumatic Brain Injury(s)
June 5-6, 2019 – Washington, D.C.
Scientific Planning Committee
Each State of the Science Summit is curated by a unique Scientific Planning Committee.
Step 1 of the Brain Trauma Blueprint Framework involves Identification of the Problem a roadmap is being established to solve. The first roadmap focus was “Paths to Treatment for Chronic TBI”.
In Step 2 of the BTB Framework, we assembled a Scientific Planning Committee (SPC) comprised of cross-sector advisors selected due to their deep expertise, flexible and innovative thought leadership, and the ability to stimulate the ecosystem with creative ideas and processes. This Committee was tasked with the identification of Failure Modes and Knowledge Gaps and the direction of a state-of-the-science literature review for core domains identified.
We collectively defined the scope of this initial roadmapping effort into six prioritized research domains, each possessing significant gaps in knowledge that require a multi-dimensional approach to bridge: (1) epidemiology of chronic effects of TBI, (2) preclinical and translational science, (3) patient phenotypes/biotypes, (4) biomarker development, (5) clinical trials, and (6) implementation science.
For Step 3, the SPC presented core findings and recommendations at a broader stakeholder Summit convening > 200 additional experts to provide input, debate, and participate in road-mapping exercises to build upon the literature and generate a consensus of priorities.